WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene_protein-coding, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_V$SRF_C       ID:DB_ID:1997
C=207; O=15; E=1.72; R=8.70; rawP=2.17e-10; adjP=1.05e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158050 NA DUSP2 dual specificity phosphatase 2 1844 ENSG00000158050
2  ENSG00000160888 NA IER2 immediate early response 2 9592 ENSG00000160888
3  ENSG00000139318 NA DUSP6 dual specificity phosphatase 6 1848 ENSG00000139318
4  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
5  ENSG00000142871 NA CYR61 cysteine-rich, angiogenic inducer, 61 3491 ENSG00000142871
6  ENSG00000123358 NA NR4A1 nuclear receptor subfamily 4, group A, member 1 3164 ENSG00000123358
7  ENSG00000171223 NA JUNB jun B proto-oncogene 3726 ENSG00000171223
8  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
9  ENSG00000163795 NA ZNF513 zinc finger protein 513 130557 ENSG00000163795
10  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
11  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
12  ENSG00000175592 NA FOSL1 FOS-like antigen 1 8061 ENSG00000175592
13  ENSG00000138166 NA DUSP5 dual specificity phosphatase 5 1847 ENSG00000138166
14  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877
15  ENSG00000099985 NA OSM oncostatin M 5008 ENSG00000099985


Database:Transcription Target       Name:hsa_GTGACGY_V$E4F1_Q6       ID:DB_ID:2412
C=641; O=24; E=5.34; R=4.49; rawP=7.49e-10; adjP=1.81e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
2  ENSG00000105722 NA ERF Ets2 repressor factor 2077 ENSG00000105722
3  ENSG00000123358 NA NR4A1 nuclear receptor subfamily 4, group A, member 1 3164 ENSG00000123358
4  ENSG00000148339 NA SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 114789 ENSG00000148339
5  ENSG00000187742 NA SECISBP2 SECIS binding protein 2 79048 ENSG00000187742
6  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
7  ENSG00000169045 NA HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 3187 ENSG00000169045
8  ENSG00000134107 NA BHLHE40 basic helix-loop-helix family, member e40 8553 ENSG00000134107
9  ENSG00000131013 NA PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 85313 ENSG00000131013
10  ENSG00000161265 NA U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 199746 ENSG00000161265
11  ENSG00000138166 NA DUSP5 dual specificity phosphatase 5 1847 ENSG00000138166
12  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877
13  ENSG00000136450 NA SRSF1 serine/arginine-rich splicing factor 1 6426 ENSG00000136450
14  ENSG00000142871 NA CYR61 cysteine-rich, angiogenic inducer, 61 3491 ENSG00000142871
15  ENSG00000136244 NA IL6 interleukin 6 (interferon, beta 2) 3569 ENSG00000136244
16  ENSG00000171223 NA JUNB jun B proto-oncogene 3726 ENSG00000171223
17  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
18  ENSG00000136527 NA TRA2B transformer 2 beta homolog (Drosophila) 6434 ENSG00000136527
19  ENSG00000153234 NA NR4A2 nuclear receptor subfamily 4, group A, member 2 4929 ENSG00000153234
20  ENSG00000064995 NA TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 6882 ENSG00000064995
21  ENSG00000142178 NA SIK1 salt-inducible kinase 1 150094 ENSG00000142178
22  ENSG00000198783 NA ZNF830 zinc finger protein 830 91603 ENSG00000198783
23  ENSG00000185022 NA MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 23764 ENSG00000185022
24  ENSG00000120129 NA DUSP1 dual specificity phosphatase 1 1843 ENSG00000120129


Database:Transcription Target       Name:hsa_V$CREBP1_Q2       ID:DB_ID:1970
C=252; O=15; E=2.10; R=7.14; rawP=3.30e-09; adjP=5.32e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173276 NA ZNF295 zinc finger protein 295 49854 ENSG00000173276
2  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
3  ENSG00000105722 NA ERF Ets2 repressor factor 2077 ENSG00000105722
4  ENSG00000148339 NA SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 114789 ENSG00000148339
5  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
6  ENSG00000153234 NA NR4A2 nuclear receptor subfamily 4, group A, member 2 4929 ENSG00000153234
7  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
8  ENSG00000142178 NA SIK1 salt-inducible kinase 1 150094 ENSG00000142178
9  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
10  ENSG00000167604 NA NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 84807 ENSG00000167604
11  ENSG00000161265 NA U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 199746 ENSG00000161265
12  ENSG00000185022 NA MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 23764 ENSG00000185022
13  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877
14  ENSG00000120129 NA DUSP1 dual specificity phosphatase 1 1843 ENSG00000120129
15  ENSG00000136450 NA SRSF1 serine/arginine-rich splicing factor 1 6426 ENSG00000136450


Database:Transcription Target       Name:hsa_V$SRF_01       ID:DB_ID:1953
C=49; O=8; E=0.41; R=19.59; rawP=6.63e-09; adjP=8.02e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160888 NA IER2 immediate early response 2 9592 ENSG00000160888
2  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
3  ENSG00000171223 NA JUNB jun B proto-oncogene 3726 ENSG00000171223
4  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
5  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
6  ENSG00000175592 NA FOSL1 FOS-like antigen 1 8061 ENSG00000175592
7  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
8  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877


Database:Transcription Target       Name:hsa_V$E4F1_Q6       ID:DB_ID:2207
C=283; O=15; E=2.36; R=6.36; rawP=1.58e-08; adjP=1.53e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173276 NA ZNF295 zinc finger protein 295 49854 ENSG00000173276
2  ENSG00000105722 NA ERF Ets2 repressor factor 2077 ENSG00000105722
3  ENSG00000142871 NA CYR61 cysteine-rich, angiogenic inducer, 61 3491 ENSG00000142871
4  ENSG00000123358 NA NR4A1 nuclear receptor subfamily 4, group A, member 1 3164 ENSG00000123358
5  ENSG00000148339 NA SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 114789 ENSG00000148339
6  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
7  ENSG00000161960 NA EIF4A1 eukaryotic translation initiation factor 4A1 1973 ENSG00000161960
8  ENSG00000153234 NA NR4A2 nuclear receptor subfamily 4, group A, member 2 4929 ENSG00000153234
9  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
10  ENSG00000142178 NA SIK1 salt-inducible kinase 1 150094 ENSG00000142178
11  ENSG00000161265 NA U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 199746 ENSG00000161265
12  ENSG00000185022 NA MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 23764 ENSG00000185022
13  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877
14  ENSG00000120129 NA DUSP1 dual specificity phosphatase 1 1843 ENSG00000120129
15  ENSG00000136450 NA SRSF1 serine/arginine-rich splicing factor 1 6426 ENSG00000136450


Database:Transcription Target       Name:hsa_V$ATF_01       ID:DB_ID:1856
C=254; O=14; E=2.12; R=6.62; rawP=2.97e-08; adjP=2.40e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173276 NA ZNF295 zinc finger protein 295 49854 ENSG00000173276
2  ENSG00000105722 NA ERF Ets2 repressor factor 2077 ENSG00000105722
3  ENSG00000142871 NA CYR61 cysteine-rich, angiogenic inducer, 61 3491 ENSG00000142871
4  ENSG00000148339 NA SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 114789 ENSG00000148339
5  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
6  ENSG00000136527 NA TRA2B transformer 2 beta homolog (Drosophila) 6434 ENSG00000136527
7  ENSG00000153234 NA NR4A2 nuclear receptor subfamily 4, group A, member 2 4929 ENSG00000153234
8  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
9  ENSG00000142178 NA SIK1 salt-inducible kinase 1 150094 ENSG00000142178
10  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
11  ENSG00000185022 NA MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 23764 ENSG00000185022
12  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877
13  ENSG00000120129 NA DUSP1 dual specificity phosphatase 1 1843 ENSG00000120129
14  ENSG00000136450 NA SRSF1 serine/arginine-rich splicing factor 1 6426 ENSG00000136450


Database:Transcription Target       Name:hsa_V$SRF_Q4       ID:DB_ID:2286
C=219; O=13; E=1.82; R=7.12; rawP=3.96e-08; adjP=2.74e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158050 NA DUSP2 dual specificity phosphatase 2 1844 ENSG00000158050
2  ENSG00000160888 NA IER2 immediate early response 2 9592 ENSG00000160888
3  ENSG00000163132 NA MSX1 msh homeobox 1 4487 ENSG00000163132
4  ENSG00000139318 NA DUSP6 dual specificity phosphatase 6 1848 ENSG00000139318
5  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
6  ENSG00000123358 NA NR4A1 nuclear receptor subfamily 4, group A, member 1 3164 ENSG00000123358
7  ENSG00000171223 NA JUNB jun B proto-oncogene 3726 ENSG00000171223
8  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
9  ENSG00000163795 NA ZNF513 zinc finger protein 513 130557 ENSG00000163795
10  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
11  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
12  ENSG00000138166 NA DUSP5 dual specificity phosphatase 5 1847 ENSG00000138166
13  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877


Database:Transcription Target       Name:hsa_V$CREB_Q2       ID:DB_ID:1968
C=261; O=13; E=2.17; R=5.98; rawP=3.04e-07; adjP=1.84e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173276 NA ZNF295 zinc finger protein 295 49854 ENSG00000173276
2  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
3  ENSG00000105722 NA ERF Ets2 repressor factor 2077 ENSG00000105722
4  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
5  ENSG00000153234 NA NR4A2 nuclear receptor subfamily 4, group A, member 2 4929 ENSG00000153234
6  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
7  ENSG00000142178 NA SIK1 salt-inducible kinase 1 150094 ENSG00000142178
8  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
9  ENSG00000167604 NA NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 84807 ENSG00000167604
10  ENSG00000161265 NA U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 199746 ENSG00000161265
11  ENSG00000185022 NA MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 23764 ENSG00000185022
12  ENSG00000136450 NA SRSF1 serine/arginine-rich splicing factor 1 6426 ENSG00000136450
13  ENSG00000120129 NA DUSP1 dual specificity phosphatase 1 1843 ENSG00000120129


Database:Transcription Target       Name:hsa_V$SRF_Q6       ID:DB_ID:1975
C=237; O=12; E=1.97; R=6.08; rawP=7.40e-07; adjP=3.98e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158050 NA DUSP2 dual specificity phosphatase 2 1844 ENSG00000158050
2  ENSG00000163132 NA MSX1 msh homeobox 1 4487 ENSG00000163132
3  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
4  ENSG00000123358 NA NR4A1 nuclear receptor subfamily 4, group A, member 1 3164 ENSG00000123358
5  ENSG00000171223 NA JUNB jun B proto-oncogene 3726 ENSG00000171223
6  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
7  ENSG00000163795 NA ZNF513 zinc finger protein 513 130557 ENSG00000163795
8  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
9  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
10  ENSG00000175592 NA FOSL1 FOS-like antigen 1 8061 ENSG00000175592
11  ENSG00000138166 NA DUSP5 dual specificity phosphatase 5 1847 ENSG00000138166
12  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877


Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2223; O=40; E=18.52; R=2.16; rawP=1.85e-06; adjP=8.95e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170049 NA KCNAB3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 9196 ENSG00000170049
2  ENSG00000139318 NA DUSP6 dual specificity phosphatase 6 1848 ENSG00000139318
3  ENSG00000120738 NA EGR1 early growth response 1 1958 ENSG00000120738
4  ENSG00000124193 NA SRSF6 serine/arginine-rich splicing factor 6 6431 ENSG00000124193
5  ENSG00000130164 NA LDLR low density lipoprotein receptor 3949 ENSG00000130164
6  ENSG00000179388 NA EGR3 early growth response 3 1960 ENSG00000179388
7  ENSG00000169045 NA HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 3187 ENSG00000169045
8  ENSG00000154734 NA ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 9510 ENSG00000154734
9  ENSG00000134107 NA BHLHE40 basic helix-loop-helix family, member e40 8553 ENSG00000134107
10  ENSG00000170144 NA HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 220988 ENSG00000170144
11  ENSG00000108342 NA CSF3 colony stimulating factor 3 (granulocyte) 1440 ENSG00000108342
12  ENSG00000161547 NA SRSF2 serine/arginine-rich splicing factor 2 6427 ENSG00000161547
13  ENSG00000171223 NA JUNB jun B proto-oncogene 3726 ENSG00000171223
14  ENSG00000125740 NA FOSB FBJ murine osteosarcoma viral oncogene homolog B 2354 ENSG00000125740
15  ENSG00000138668 NA HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 3184 ENSG00000138668
16  ENSG00000136689 NA IL1RN interleukin 1 receptor antagonist 3557 ENSG00000136689
17  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
18  ENSG00000099985 NA OSM oncostatin M 5008 ENSG00000099985
19  ENSG00000173846 NA PLK3 polo-like kinase 3 1263 ENSG00000173846
20  ENSG00000128342 NA LIF leukemia inhibitory factor 3976 ENSG00000128342
21  ENSG00000114315 NA HES1 hairy and enhancer of split 1, (Drosophila) 3280 ENSG00000114315
22  ENSG00000163132 NA MSX1 msh homeobox 1 4487 ENSG00000163132
23  ENSG00000155090 NA KLF10 Kruppel-like factor 10 7071 ENSG00000155090
24  ENSG00000158859 NA ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 9507 ENSG00000158859
25  ENSG00000105722 NA ERF Ets2 repressor factor 2077 ENSG00000105722
26  ENSG00000011422 NA PLAUR plasminogen activator, urokinase receptor 5329 ENSG00000011422
27  ENSG00000167565 NA SERTAD3 SERTA domain containing 3 29946 ENSG00000167565
28  ENSG00000161960 NA EIF4A1 eukaryotic translation initiation factor 4A1 1973 ENSG00000161960
29  ENSG00000100941 NA PNN pinin, desmosome associated protein 5411 ENSG00000100941
30  ENSG00000170345 NA FOS FBJ murine osteosarcoma viral oncogene homolog 2353 ENSG00000170345
31  ENSG00000122877 NA EGR2 early growth response 2 1959 ENSG00000122877
32  ENSG00000143878 NA RHOB ras homolog family member B 388 ENSG00000143878
33  ENSG00000147274 NA RBMX RNA binding motif protein, X-linked 27316 ENSG00000147274
34  ENSG00000134758 NA RNF138 ring finger protein 138, E3 ubiquitin protein ligase 51444 ENSG00000134758
35  ENSG00000108654 NA DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1655 ENSG00000108654
36  ENSG00000198576 NA ARC activity-regulated cytoskeleton-associated protein 23237 ENSG00000198576
37  ENSG00000152795 NA HNRPDL heterogeneous nuclear ribonucleoprotein D-like 9987 ENSG00000152795
38  ENSG00000076604 NA TRAF4 TNF receptor-associated factor 4 9618 ENSG00000076604
39  ENSG00000175592 NA FOSL1 FOS-like antigen 1 8061 ENSG00000175592
40  ENSG00000131051 NA RBM39 RNA binding motif protein 39 9584 ENSG00000131051




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).